With a bright future in China plant extract industry calls high-quality exports

At the recent Eighth World Exhibition on China’s pharmaceutical bulk drugs, a phenomenon caused by the exhibition to the attention of: plant extracts theme at the show are very active in the relevant exhibitors not only much larger scale, but also the special open the area of plant extracts and forums. Looking back to the first half of this year, European and American merchants Canton plant extracts in China exhibition stand sits a competing business inquiry of the grand, these are shows that the plant extract-selling products in the United States and Europe to promote the domestic industry and export of plant extracts Trade also became active.

It is reported that paclitaxel, camptothecin, stone Class A shirt made of alkali plant extract products as source of supply, simply can not meet foreign orders, while the Chinese wolfberry, Rhodiola, Ganoderma lucidum, Angelica, Pueraria and some “new resources, plant extracts product “(Western countries generally believe that they are” plant extract new resources “products) are frequently patronized in demand for foreign goods.

However, while the prospect to look forward to, but our country’s export value-added plant extracts are still relatively low, such as artemisinin, ginkgo biloba extract, solanesol and so on, because the purification technology behind the quality of export products and often result in lower profits and the huge loss of market share, etc., especially in Japan, Korea and other Asian neighbors, China plant extract industry burgeoned, today, this export is clearly need to reflect the passive situation.

Artemisinin: Production and Marketing of balance, export licensing system introduced brewing

Artemisinin malaria due to inhibition of the effect of reproduction is better than using the years of anti-malaria drug chloroquine and pyrimethamine old, became the World Health Organization designated for malaria endemic areas of Africa the main antimalarial drugs used at present no Other plant sources of antimalarial drugs (quinine, except) to replace its market position.

World Health Organization in 2004, has published an analysis of the global malaria market, according to the report described the prospects of prevailing are about 350 million people worldwide suffer from malaria projections, total world demand for artemisinin to 2010 300 tons of agent sales will reach more than 1.5 billion dollars. Thus, the provinces in southwest China set off a wave of plant Artemisia annua.

But in fact, after several years, the international market demand for artemisinin-based API is not as high as the WHO forecast. In 2004, China is only less than 10 artemisinin extraction plant, the national annual production of as few as 18 tons of artemisinin. Over-optimistic forecasts in the stimulation of artemisinin, the domestic situation of artemisinin production has herd phenomenon. To the end of 2006, the National artemisinin extraction plant has swelled to nearly 100, to produce nearly 80 tons of crude artemisinin.

Such a huge domestic production simply can not digest, can only export overseas, and the right sales agent artemisinin is nearly the hands of the hands of Novartis in China can only export cheap drug artemisinin raw crude. In 2004, the artemisinin drug export price of raw materials are still 7,000 yuan per kilogram, while the end of 2007 plummeted to only 1,300 yuan per kg, a lot of manufacturers of artemisinin losses. The company stopped buying because many of Artemisia annua and even rot in the ground.

It is reported that artemisinin in exports is not due to poor quality of our products, but experience from Vietnam, Thailand and other Southeast Asian countries and Kenya and other African countries, the impact of exports of low-cost artemisinin, these countries are also vigorously cultivated flower Artemisia and extract artemisinin.

Nevertheless, artemisinin as an international market only a natural antimalarial drugs, the market outlook remains very bright. The only one approved by WHO in China has its own export of artemisinin preparations qualified Guilin Pharmaceutical Company, last year exported about 15 million U.S. dollars of artemisinin tablets, is expected to Guilin Pharmaceutical exports this year will exceed last year the number of artemisinin tablets.

In view of the domestic manufacturers competing drug artemisinin lower prices of raw materials export status of artemisinin, China Ministry of Commerce is working with the Medicines & Health Products Import and Export Chamber of Commerce to work out, “Administration of artemisinin-based exports.”

According to reports, the future will follow the Ministry of Commerce of ephedrine, licorice extract export export license system as artemisinin, the enterprise can only obtain a permit of foreign export of raw artemisinin drugs. I believe that through effective control measures, concerned to restore the export of artemisinin leading to lower prices adversely affected the interests of the situation, thus contributing to the export of raw artemisinin to healthy and orderly.

Solanesol: “hot” is not expensive, new technology is expected to turn the tide

But the rise of solanesol short history of ten years, but has become the most popular on the international market of plant extracts, as solanesol a variety of important health-care synthetic drugs such as coenzyme Q10, vitamin K2 and other key intermediates, in particular, coenzyme Q10 with anti-acute myocardial infarction and the clinical effect of anti-viral, popular in the international market, driven Solanesol tight. Are abroad have developed a variety of raw materials to solanesol anti-cardiovascular disease, cancer and treatment of diseases such as gastric ulcer drug.

Since 2005, solanesol plant extracts in the international market rapidly heating up, according to estimates, the world of high purity solanesol total demand of about 5,000 tons. In fact, the tobacco leaves are the source of solanesol very low content of crude solanesol, special equipment must be processed to remove impurities, and more than 90% purity can be raised to synthetic coenzyme Q10 as a raw material or vitamin K2. China’s exports of about 3,000 tons annually in recent years about 20% of the content of crude solanesol, the export price of only 9 per ton of 70 000 million, while the international market of high purity solanesol average price per ton 48 million or more. This seems export crude solanesol is some more harm than good. In recent years, solanesol exception in the international market sells off products basically the number of how many, Japan, the United States and other Western countries, manufacturers are importing large quantities of crude from China solanesol, home finishing as high purity and then sold Solanesol international market and even sold back to China, where the difference is astounding.

The good news is the last note of domestic colleges and universities, led by Nanjing Normal University researchers have invented a crude refining medicine solanesol grade high purity with solanesol new technology, intellectual property rights the next few years is expected to be of high purity solanesol exports, thus breaking the monopoly of Japanese and U.S. high-purity Solanesol international market situation, then, to cheap solanesol domestic crude exports for foreign exchange situation will completely change.

Hypericin: glow “second spring”, the potential of encroaching upon paclitaxel

Hypericin as a good antidepressant effect has been received by the European Pharmacopoeia contains herbs, their preparations by excellent sales in the European market, annual sales of approximately more than 300 million U.S. dollars. United States, less hypericin market, only 20 million ~ 30 million U.S. dollars in annual sales.

However, hypericin so much attention again in 2004 the worldwide outbreak of avian flu. Roche was the only production of “Tamiflu” is effective in treating bird flu, but the price of Tamiflu is too expensive, not suitable for low-income people in many of China’s national conditions, for which the domestic TCM research institutes began in search of anti-Chinese herbal medicine Avian flu drug, has finally found the extract of Hypericum perforatum hypericin, one of the culprits causing avian influenza – H5N1 has a strong inhibitory effect. The news spread abroad, immediately aroused strong interest in the United States and other developed countries. Since 2005, China’s first export of hypericin to Vietnam, Thailand, South Korea, Indonesia, bird flu well against Asian countries, and later exported to Japan and the United States. It is reported that China’s exports of non-pharmaceutical grade hypericin average price of crude 120 yuan per kilogram.

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